<b>Mixed models in cerebral ischemia study
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چکیده
منابع مشابه
Progress Review Rodent Models of Cerebral Ischemia
The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury—both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relatively low cost, are highly suitable for the investigation of cerebral ischemia and have been widely em...
متن کاملNonhuman primate models of focal cerebral ischemia
Rodents have been widely used in the production of cerebral ischemia models. However, successful therapies have been proven on experimental rodent stroke model, and they have often failed to be effective when tested clinically. Therefore, nonhuman primates were recommended as the ideal alternatives, owing to their similarities with the human cerebrovascular system, brain metabolism, grey to whi...
متن کاملThe Role of Peroxisome Proliferator Activator Receptor Alpha in Cerebral Ischemia-Reperfusion Injury; a Review Study
Peroxisome proliferator-activated receptor alpha (PPAR-α), which belongs to the nuclear receptor family of ligand-activated transcription factors, was first described as gene regulators for metabolic pathways including lipid metabolism, insulin sensitivity, and glucose homeostasis. Were raised. This nuclear receptor is widely expressed in various tissues, providing a wide range of effects to st...
متن کاملCerebral Ischemia/Reperfusion Injury in the Hyperthyroid Rat
Background: Hyperthyroidism as a risk factor for stroke is not conclusive. There are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. This study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. Methods: Two groups of hyperthyroid (HT) and control euthyroid rats of equal numbers ...
متن کاملCerebral Ischemia-Reperfusion Injuries in Vanadyl-Treated Diabetic Rats
Background: Ischemic stroke recovery is poor in diabetic mellitus (DM). Vanadium compounds (vanadium) relieve DM signs, but their influences on cerebral ischemia/reperfusion injury (I/RI) are inconclusive. Herein, the intensity of I/RI was inspected in vanadium-treated DM rats.Methods: Rats made diabetic with a single intravenous dose of streptozocin (39 mg/kg). Normal and DM rats used water or...
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ژورنال
عنوان ژورنال: Acta Scientiarum. Technology
سال: 2016
ISSN: 1807-8664,1806-2563
DOI: 10.4025/actascitechnol.v38i3.28314